Management of Peutz-Jeghers syndromes in children and adolescents (2018)

Peutz-jeghers syndrome (PJS) is a well-described inherited syndrome, characterised by the

development of gastrointestinal polyps and characteristic mucocutaneous freckling.

Development of small bowel intestinal polyps may lead to intussusception in children may

require emergency laparotomy with potential loss of bowel. Gastrointestinal (GI) polyps may

lead to bleeding and anaemia. This ESPGHAN position paper provides a guide for diagnosis,

assessment and management of PJS in children and adolescents and guidance on avoiding

complications from PJS or from the endoscopic procedures performed on these patients.

Journal of Pediatric Gastroenterology and Nutrition

PJS clinical trial / research in Beijing, China (Rapamycin)

 Peking Union Medical College Hospital, Chinese Academy of Medicine Sciences, Beijing, China

Contact: Jiaolin Zhou, MD    conniezhjl@yahoo.com 

U.S. National Library of Medicine

Rapamycin: one drug, many effects

National Institue of health

Peutz-Jeghers Syndrome

Cancer.net

Peutz-Jeghers Syndrome

John Hopkins Medicine

Peutz-Jeghers Syndrome

U.S. National Library of Medicine

Colon Cancer Screening, PJS

The River Reporter